The book consists of five parts. Part One has two chapters. One chapter describes the history of acupuncture in China, and another in the United States. Part Two also has two chapters. One chapter is used to discuss the absurd concepts and heretic suppositions of Chinese medicine, and another is devoted specifically to non-scientific theories of the traditional acupuncture. These four chapters should be comprehensible to all readers with or without a sophisticated medical background. Such a sophistication may be required to fully understand the rest of the book.There are five chapters in Part Three. Their purposes are to provide established knowledges in the basic science of medicine, including anatomy, physiology and biochemistry, for interpreting acupuncture. After a thorough understanding of the basic sciences in acupuncture, it will be possible to realize what acupuncture can be used for the clinical applications which are discussed in Part Four. Acupuncture can have good and excellent results for certain patients with a clinical condition diagnosed, and yet, the same conditions in others patients may not be benefited by the same treatments. Thus, patients are categorized into different groups each of which will have a chapter to explain why acupuncture will work and why it will not. Four chapter are composed to discuss different therapeutical results in acupuncture treatments. Part Five is written intended for scientific research. One chapter offers suggestions for clinical investigations using acupuncture as a vehicle in signing research protocols. The last chapter speculates on the possibility to use information described in this book for studies of pain in terms of basic medical sciences.